Steroids and derivatives
TARGETMOL CHEMICALS INC Estrone sulfate potassium 25MG
Also available in 1 mL, 2 mg, 5 mg, 10 mg and bulk. Please contact Fisher for quotes. Estrone sulfate potassium is an estrogen ester and conjugate, a natural endogenous steroid. Purity 99.05%
Medchemexpress LLC Estrone O-sulfamate | 148672-09-7 | 99.99% | C18H23NO4S | 25 MG
Estrone O-sulfamate is a potent inhibitor of steroid sulfatase (STS). It exhibits inhibitory activity against STS in placental microsomes (P.M.) preparations and MCF-7 cells, with IC50 values of 18 nM and 0.83 nM, respectively. This compound is suitable for use in cancer research.
- Potent steroid sulfatase (STS) inhibitor
- Inhibits STS in placental microsomes (P.M.) preparations
- Inhibits STS in MCF-7 cells
- Suitable for cancer research
Medchemexpress LLC Estrone O-sulfamate | 148672-09-7 | 99.99% | C18H23NO4S | 100 MG
Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. It has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. This compound can be used for the research of cancer.
- Potent steroid sulfatase (STS) inhibitor.
- Inhibitory activity in placental microsomes (P.M.) preparation with an IC50 of 18 nM.
- Inhibitory activity in MCF-7 cells with an IC50 of 0.83 nM.
- Suitable for cancer research.
Medchemexpress LLC Estrone | 53-16-7 | 99.9% | 5 G
Estrone (E1) is a natural estrogenic hormone and the primary endogenous estrogen in postmenopausal women. It is produced by several tissues, particularly adipose tissue, through the aromatization of androstenedione.
- Natural estrogenic hormone and endogenous estrogen
- Produced in adipose tissue
- Targets estrogen receptor and ERR
- Relevant for endocrinology and cancer research
- Categorized as a natural product, inhibitor, or agonist
- Involved in vitamin D related and nuclear receptor pathways
- Involved in metabolic enzyme and protease pathways
- Stable as powder at -20°C for 3 years and 4°C for 2 years
- Stable in solvent at -80°C for 6 months and -20°C for 1 month
- Soluble in DMSO
Medchemexpress LLC Estrone | 53-16-7 | 100.0% | 1 G
Estrone (E1) is a natural estrogenic hormone and the main representative of endogenous estrogens. It is produced by several tissues, particularly adipose tissue, and results from the aromatization of androstenedione in fat cells. It is the main endogenous estrogen in postmenopausal women.
- Also known as E1 or Oestrone.
- Classified as a human endogenous metabolite.
- Appears as a white to off-white solid.
- Has a molecular weight of 270.37 and a chemical formula of C18H22O2.
- Insoluble in H2O (< 0.1 mg/mL) but soluble in DMSO (25 mg/mL).
- For research use only.
Medchemexpress LLC Estrone sulfate potassium | 1240-04-6 | MFCD00056410 | 99.5% | 388.52 | C18H21KO5S | 5 MG
Estrone sulfate potassium is the potassium salt of estrone sulfate, an endogenous estrogen conjugate supplied for laboratory research. It is available as a high-purity solid and as a DMSO solution for in vitro studies, and is intended for research use only.
- High purity 99.45%.
- Molecular weight 388.52 and formula C18H21KO5S.
- Available in multiple sizes, including 5 mg, and as a 10 mM solution in DMSO.
- Soluble in DMSO for preparation of stock solutions.
- Supplied for research use only; not for human or clinical use.
- May be restricted or controlled in some territories.
Medchemexpress LLC Estrone O-sulfamate | 148672-09-7 | 99.99% | C18H23NO4S | 1 MG
Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. It can be used for cancer research.
- Potent steroid sulfatase (STS) inhibitor
- Demonstrates inhibitory activity in placental microsomes (P.M.) and MCF-7 cells
- Applicable for cancer research
Medchemexpress LLC Estrone 3-glucuronide sodium | 15087-01-1 | 98.3% | 468.47 | 1 MG
Estrone 3-glucuronide sodium is a metabolite of 17-Estradiol. It is used as a standard to estimate estrone conjugate (E1Cs) from urine samples by enzyme immunoassays (EIAs) and is the reference standard used in assays that measure urinary E1C, a key marker for tracking the transition to the luteal phase.
- Estimates estrone conjugate (E1Cs) from urine samples
- Used in enzyme immunoassays (EIAs)
- Reference standard in assays measuring urinary E1C
- Key marker for tracking the transition to the luteal phase
- Useful in urogenital, urologic, and endocrinology research
Medchemexpress LLC Estrone 3-methyl ether | 1624-62-0 | 97.38% | C19H24O2 | 5 MG
Estrone 3-methyl ether is a synthetic intermediate used in the synthesis of estrogen receptor modulators.
- Used in the synthesis of estrogen receptor modulators
- Molecular weight: 284.39
- Molecular formula: C19H24O2
- CAS number: 1624-62-0
- Purity: 97.38%
- Appearance: Solid, white to off-white
- Storage (Powder): -20°C for 3 years; 4°C for 2 years
- Storage (In solvent): -80°C for 6 months; -20°C for 1 month
Cayman Chemical Estrone Steroid Hormones
A primary, naturally-occurring estrogen; serum concentrations in premenopausal women fluctuate according to the menstrual cycle; becomes the most predominant estrogen in postmenopausal women; binding affinities to ERα and ERβ are ~60% and ~37% relative to estradiol
Medchemexpress LLC Estrone sulfate (sodium) | 438-67-5 | 99.8% | 372.41 | 25 MG
Estrone sulfate sodium is an inactive endogenous estrogen. It can be converted into Estrone and Estradiol and is a substrate of the OATP1B3 transporter. This compound stimulates the growth of nitrosomethylurea-induced mammary tumors and colony formation of dispersed nitrosomethylurea mammary cells, with conversion to Estrone and Estradiol occurring both in vivo and in vitro.
- Can be converted into Estrone and Estradiol.
- Substrate of the OATP1B3 transporter.
- Stimulates mammary tumor growth in ovariectomized rats.
- Applicable to breast cancer-related research.
TARGETMOL CHEMICALS INC Estrone sulfate sodium 25MG
Also available in 2 mg, 5 mg, 10 mg, 50 mg and bulk. Please contact Fisher for quotes. Estrone sulfate sodium (17beta-Estrone 3-sulfate) is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone . Estrone sulfate sodium has been investigated as a ligand for targeting organic anion transporting polypeptides f Purity 98%